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Related Concept Videos

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Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
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Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers, unexplained...
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Endoscopic Ultrasound (EUS):

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Related Experiment Video

Updated: May 7, 2026

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
07:05

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation

Published on: December 15, 2017

Advanced endoscopic imaging techniques in Crohn's disease.

Gian Eugenio Tontini1, Maurizio Vecchi2, Markus F Neurath3

  • 1Department of Medicine I, University of Erlangen-Nuremberg, Germany; Gastroenterology and Digestive Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese, Italy.

Journal of Crohn'S & Colitis
|October 2, 2013
PubMed
Summary

Advanced endoscopic imaging techniques, including device-assisted enteroscopy (DAE) and small-bowel capsule endoscopy (SBCE), significantly improve Crohn's disease (CD) diagnosis and characterization. These innovations enhance dysplasia detection and mucosal healing assessment beyond conventional methods.

Keywords:
Chromoendoscopy;Confocal laser endomicroscopyCrohn's diseaseDevice-assisted enteroscopyInflammatory Bowel DiseaseSmall-bowel capsule endoscopy

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Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
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Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

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Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
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Published on: December 15, 2017

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Area of Science:

  • Gastroenterology
  • Endoscopic Imaging
  • Inflammatory Bowel Disease

Background:

  • Endoscopy is crucial for Crohn's disease (CD) management, including diagnosis, surveillance, and activity assessment.
  • Device-assisted enteroscopy (DAE) and small-bowel capsule endoscopy (SBCE) have advanced small-bowel imaging.
  • New endoscopic imaging techniques aim to improve characterization of mucosal inflammation and detection of dysplasia.

Purpose of the Study:

  • To review advanced endoscopic imaging concepts for diagnosing and characterizing CD.
  • To highlight the role of novel endoscopic techniques in IBD patient care.

Main Methods:

  • Literature search on advanced endoscopy techniques in inflammatory bowel disease (IBD) patients.
  • Review of studies focusing on DAE, SBCE, chromoendoscopy, narrow band imaging, i-scan, confocal laser endomicroscopy (CLE), and endocytoscopy.

Main Results:

  • DAE and SBCE offer high diagnostic yields for deep enteroscopy but require defined roles in diagnostic algorithms.
  • Chromoendoscopy (dye-based and dye-less) and magnification enhance dysplasia detection and assessment of inflammatory activity and extent.
  • Narrow band imaging, i-scan, CLE, and endocytoscopy show promise in improving dysplasia detection, predicting inflammatory changes, assessing therapeutic response, and evaluating mucosal activity.

Conclusions:

  • Advances in small-bowel enteroscopy offer significant benefits for CD diagnosis and characterization.
  • New endoscopic imaging techniques improve dysplasia detection and refine mucosal healing assessment, offering insights beyond morphology.