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Updated: May 7, 2026

Generation of Integration-free Induced Pluripotent Stem Cells from Human Peripheral Blood Mononuclear Cells Using Episomal Vectors
09:45

Generation of Integration-free Induced Pluripotent Stem Cells from Human Peripheral Blood Mononuclear Cells Using Episomal Vectors

Published on: January 1, 2017

Generation of induced pluripotent stem cells with high efficiency from human umbilical cord blood mononuclear cells

Juan Wang1, Qi Gu, Jie Hao

  • 1State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; College of Life Science, Northeast Agricultural University of China, Harbin 150030, China.

Genomics, Proteomics & Bioinformatics
|October 2, 2013
PubMed

Keywords:
Dox-inducible lentiviral systemHuman UCBMCsHuman iPSCs

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
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Somatic cells are...