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Peri-dialytic hypertension and hypotension: another U-shaped BP-outcome association
11] Department of Medicine, Duke University, Durham, North Carolina, USA [2] Quintiles Global Clinical Research Institute, Morrisville, North Carolina, USA.
Abstract:
Park et al. performed a retrospective analysis of a large hemodialysis cohort to describe the relationship between pre- to postdialysis changes in BP and mortality. Their study demonstrated adverse outcomes associated both with large decreases and with any increase in blood pressure pre- to postdialysis. Although limitations exist in this analysis, which lacked intradialytic blood pressure measurements, the results support the ongoing concern about the potential adverse hemodynamic stress associated with conventional three-times-weekly hemodialysis.
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