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Updated: May 7, 2026
12:23
Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Oral hemorrhagic blister: an enigma
Bm Shashikumar1, R Raghunatha Reddy, Mr Harish
1Department of Skin and STD, Mandya Institute of Medical Sciences, Mandya, Karnataka, India.
Indian Journal of Dermatology
|October 2, 2013
Summary
Angina bullosa hemorrhagica (ABH) presents as sudden, spontaneous blood-filled blisters on the oral mucosa. This case series explores ABH, including an idiopathic case and one linked to chronic renal failure requiring hemodialysis.
Area of Science:
- Oral Medicine
- Dermatology
- Pathology
Background:
- Angina bullosa hemorrhagica (ABH) is a rare oral mucosal disorder.
- Its etiology remains largely unknown.
- Characterized by spontaneous, blood-filled blisters on the oral mucosa.
Purpose of the Study:
- To report two distinct cases of Angina bullosa hemorrhagica.
- To highlight the varied clinical presentations and potential associations of ABH.
Main Methods:
- Case report methodology.
- Clinical presentation and histopathological examination of oral mucosal lesions.
- Review of patient medical history, including comorbidities.
Main Results:
- Case 1: Idiopathic Angina bullosa hemorrhagica.
- Case 2: Angina bullosa hemorrhagica associated with chronic renal failure and hemodialysis.
- Histopathology consistent with subepithelial blister formation and erythrocyte presence.
Conclusions:
- Angina bullosa hemorrhagica can occur idiopathically.
- Association with chronic renal failure and hemodialysis is noted.
- Further research into ABH etiology and management is warranted.
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