Nosocomial urinary tract aspergilloma in an immunocompetent host: an unusual occurrence

Archana Singal1, Chander Grover, Deepika Pandhi

  • 1Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital, University of Delhi, Delhi, India.

Insights

Urinary tract infections (UTIs) caused by Aspergillus flavus are rare, especially in immunocompetent individuals. This case report highlights a successful treatment of Aspergillus flavus UTI in an immunocompetent man using itraconazole.

Area of Science:

  • Mycology
  • Urology
  • Infectious Diseases

Background:

  • Fungal urinary tract infections (UTIs) often occur after antibiotic use, catheterization, or instrumentation.
  • Candida species are the most common fungal pathogens causing UTIs.
  • Aspergillus flavus UTIs are typically seen in immunocompromised patients.

Purpose of the Study:

  • To report a rare case of Aspergillus flavus UTI in an immunocompetent individual.
  • To describe the clinical presentation and successful management of this infection.

Main Methods:

  • Case report of a 32-year-old immunocompetent male patient.
  • Diagnosis of urinary tract infection caused by Aspergillus flavus.
  • Treatment with a broad-spectrum antifungal agent, itraconazole.

Main Results:

  • The patient presented with symptomatic UTI, abdominal pain, and passage of fungal masses.
  • Aspergillus flavus was identified as the causative agent.
  • Successful treatment was achieved with a prolonged course of itraconazole.

Conclusions:

  • Aspergillus flavus can cause symptomatic UTIs in immunocompetent hosts, even after instrumentation.
  • Prompt diagnosis and antifungal treatment, such as with itraconazole, are crucial for successful outcomes.

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