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Related Concept Videos

Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

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Related Experiment Video

Updated: May 7, 2026

Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia
08:55

Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia

Published on: May 18, 2018

Ischemic colitis.

T Mohanapriya1, K Balaji Singh, T Arulappan

  • 1Surgery, Sri Ramachandra Hospital, No.1, Ramachandra nagar, Porur, Chennai 600116 India.

The Indian Journal of Surgery
|October 2, 2013
PubMed
Summary
This summary is machine-generated.

Ischemic colitis, a subtle gastrointestinal disease, presents unique diagnostic and treatment challenges. This review details its varied presentations and management strategies for better patient outcomes.

Keywords:
Colon ischemiaIschemic colitisUniversal fulminant colitis

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Last Updated: May 7, 2026

Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia
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Published on: May 18, 2018

Murine Colitis Modeling using Dextran Sulfate Sodium (DSS)
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Published on: January 19, 2010

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Area of Science:

  • Gastroenterology
  • Vascular Medicine
  • Internal Medicine

Background:

  • Ischemic diseases of the gastrointestinal tract are common yet challenging to diagnose and treat.
  • Colon ischemia, specifically, often presents subtly, complicating early detection.
  • Effective management requires understanding diverse clinical manifestations.

Purpose of the Study:

  • To review the various presentation patterns of ischemic colitis.
  • To outline current management strategies for ischemic colitis.
  • To improve the diagnostic and therapeutic approach to this condition.

Main Methods:

  • Systematic review of existing literature on ischemic colitis.
  • Analysis of clinical presentations and diagnostic findings.
  • Evaluation of treatment outcomes for different management approaches.

Main Results:

  • Ischemic colitis exhibits a wide spectrum of clinical presentations, from mild abdominal pain to severe rectal bleeding.
  • Diagnostic challenges are highlighted due to non-specific symptoms.
  • Management strategies vary based on severity, including conservative measures and surgical interventions.

Conclusions:

  • Recognizing the diverse presentations of ischemic colitis is crucial for timely diagnosis.
  • Tailored management plans are essential for optimizing patient recovery.
  • Further research may elucidate more precise diagnostic markers and therapeutic targets.