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Updated: May 7, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Cutaneous mercury granuloma
Kalpana A Bothale1, Sadhana D Mahore, Sushil Pande
1Department of Pathology, N. K. P. Salve Institute of Medical Sciences and Research Center, Nagpur, Maharashtra, India.
Abstract:
Cutaneous mercury granuloma is rarely encountered. Clinically it may pose difficulty in diagnosis. Here, we report a 23-year-old male presented with erythematous, nodular lesions over the forearm and anterior aspect of chest wall. Metallic mercury in tissue sections appear as dark black, opaque, spherical globules of varying size and number. They are surrounded by granulomatous foreign-body reaction. It is composed of foreign body giant cells and mixed inflammatory infiltrate composed of histiocytes, lymphocytes, plasma cells, and few eosinophils.
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