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Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian Patients

Spyridoula Doukaki1, Valentina Caputo, Maria Rita Bongiorno

  • 1Department of Dermatology, University of Palermo, Via del Vespro 131, 90123 Palermo, Italy.

Dermatology Research and Practice
|October 2, 2013
PubMed

Insights

Psoriasis patients have a significantly higher cardiovascular risk compared to those without the condition. Early identification and management of cardiovascular risk factors in psoriasis is crucial for prevention.

Area of Science:

  • Dermatology
  • Cardiology
  • Epidemiology

Background:

  • Psoriasis is a prevalent inflammatory skin condition with debated links to cardiovascular disease.
  • Existing research indicates a potential increase in cardiovascular risk factors and diseases among psoriasis patients.
  • This study investigates the association between psoriasis and cardiovascular risk.

Purpose of the Study:

  • To assess the cardiovascular risk score in patients with psoriasis.
  • To explore the relationship between cardiovascular risk and specific psoriasis features.
  • To evaluate cardiovascular risk using the CUORE project risk score.

Main Methods:

  • A case-control study involving 210 psoriasis outpatients and 111 controls with other skin conditions.
  • Utilized the CUORE project risk score, designed for populations with low coronary heart disease rates.
  • Compared cardiovascular risk scores between psoriasis patients and controls.

Main Results:

  • Psoriasis patients exhibited a significantly higher CUORE project risk score than controls (6.80 ± 6.34 vs. 4.48 ± 4.38, P < 0.001).
  • Psoriasis patients face an elevated risk of major cardiovascular events compared to controls.
  • No significant correlation was found between cardiovascular risk and specific psoriasis characteristics.

Conclusions:

  • Psoriasis is associated with increased cardiovascular risk.
  • Routine screening for cardiovascular risk factors in psoriasis patients is recommended.
  • Proactive lifestyle modifications and therapeutic interventions are warranted for psoriasis patients to mitigate cardiovascular risks.

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