Sinus node dysfunction as the first manifestation of left ventricular noncompaction with multiple cardiac...

Area of Science:

• Cardiology
• Genetics
• Internal Medicine

Background:

• Left ventricular noncompaction (LVNC) is a rare, genetically diverse cardiomyopathy.
• Symptoms like dyspnea and arrhythmias often lead to late diagnosis in adulthood.
• Symptomatic sinus node dysfunction is an uncommon presentation of LVNC.

Purpose of the Study:

• To report a rare case of adult-onset LVNC.
• To highlight unusual coexistent cardiac defects in an adult LVNC patient.
• To emphasize atypical initial presentation of LVNC.

Main Methods:

• Case report of a 23-year-old female patient.
• Review of clinical presentation, echocardiography, and cardiac history.
• Analysis of coexistent cardiac anomalies and sinus node function.

Main Results:

• The patient presented with dizziness due to persistent sinus node dysfunction.
• Diagnosed with LVNC, patent ductus arteriosus, and bicuspid aortic valve.
• Demonstrated a rare combination of isolated LVNC with congenital heart defects in adulthood.

Conclusions:

• LVNC can present atypically in adulthood with sinus node dysfunction and congenital defects.
• Early diagnosis and management are crucial for patients with LVNC.
• This case expands the understanding of LVNC's varied clinical manifestations.