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A pigmented odontogenic keratocyst.

R I Macleod, K B Fanibunda, J V Soames

    The British Journal of Oral & Maxillofacial Surgery
    |June 1, 1985
    PubMed
    Summary
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    A rare pigmented odontogenic keratocyst was found in a Caucasian female. Melanocytes were identified in the basal cell layer, indicating a potential new subtype of this jaw cyst.

    Area of Science:

    • Oral pathology
    • Odontogenic cysts
    • Histopathology

    Background:

    • Odontogenic keratocysts (OKCs) are common developmental cysts of the jaw.
    • While typically non-pigmented, rare variants may present with pigmentation.
    • Understanding OKC variations is crucial for accurate diagnosis and treatment.

    Observation:

    • This report details a unique case of a pigmented odontogenic keratocyst.
    • The cyst occurred in a white Caucasian female patient.
    • Histological examination revealed the presence of melanocytes.

    Findings:

    • Melanocytes were definitively identified within the basal cell layer of the OKC.
    • Both light and electron microscopy confirmed the presence and location of these melanocytes.

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  • This finding suggests a potential melanocyte-derived component or influence in this specific OKC.

    • Implications:

    • This case expands the known spectrum of odontogenic keratocyst presentations.
    • The presence of melanocytes may warrant further investigation into the pathogenesis of pigmented OKCs.
    • This finding could influence diagnostic criteria and future research into jaw cyst development.