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Pulmonary function tests in type 2 diabetics and non-diabetic people -a comparative study
1Assistant Professor, Department of Physiology, Gsl Medical College , Rajahmundry-Andhra Pradesh, India .
Type 2 diabetes adversely affects lung function, causing a restrictive pattern. This study found reduced lung capacity (FVC, FEV1, PEFR) in diabetics compared to controls.
Area of Science:
- Pulmonary Medicine
- Diabetology
- Physiology
Background:
- Pulmonary complications of diabetes mellitus are not well-characterized.
- Type 2 diabetes is linked to macrovascular and microvascular damage.
- This study investigates the mechanical aspects of lung dysfunction in type 2 diabetes.
Purpose of the Study:
- Compare pulmonary function tests (PFTs) in type 2 diabetics and non-diabetics using spirometry.
- Assess the impact of chronic hyperglycemia on lung function and daily living activities in type 2 diabetics.
Main Methods:
- Computerized spirometry was used to measure PFTs (FVC, FEV1, FEV1/FVC%, PEFR).
- 40 type 2 diabetics (40-65 years) and 40 age/sex/BMI-matched controls participated.
- Exclusion criteria included smoking history or conditions affecting lung function.
Main Results:
- Statistically significant reductions in Forced Vital Capacity (FVC), Forced Expiratory Volume in 1 second (FEV1), and Peak Expiratory Flow Rate (PEFR) were observed in type 2 diabetics compared to controls.
- The FEV1/FVC ratio was significantly increased in type 2 diabetics.
Conclusions:
- Type 2 diabetes negatively impacts the mechanical functions of the lungs.
- The observed pattern of lung disease in type 2 diabetes is primarily restrictive.
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