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Meningitis due to Stenotrophomonas maltophilia after a Neurosurgical Procedure
Smita Sood1, Vivek Kumar Vaid, Hemant Bhartiya
1Microbiologist, Department of Laboratory Medicine, (SRL Ltd.), Fortis Escorts Hospital , Jaipur, India .
Abstract:
Stenotrophomonas maltophilia is an aerobic, glucose non- fermentative, gram negative bacillus, which is being increasingly recognized as a cause of serious infections such as bacteraemia, urinary tract infections, respiratory tract infections, skin and soft tissue infections, endocarditis, meningitis and ocular infections in hospitalized patients. The treatment of invasive S. maltophilia infections is difficult, as this pathogen shows high levels of intrinsic or acquired resistance to different antibiotics, thus reducing the options which are available for treatment. Meningitiscaused by S. maltophilia is rarely encountered and so its experience is also limited. We are describing here a case of a six months old, male child who developed meningitis caused by Stenotrophomonas maltophilia, after he underwent a neurosurgical procedure.
Insights
Stenotrophomonas maltophilia meningitis is a rare but serious infection in children, especially after neurosurgery. This case highlights the challenges in treating this difficult-to-manage bacterial infection.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Pediatric Neurology
Background:
- Stenotrophomonas maltophilia is an opportunistic pathogen increasingly associated with severe hospital-acquired infections.
- This bacterium exhibits significant intrinsic and acquired antibiotic resistance, complicating treatment strategies.
- Meningitis caused by S. maltophilia is uncommon, with limited clinical experience and data.
Purpose of the Study:
- To report a rare case of S. maltophilia meningitis in a pediatric patient following neurosurgery.
- To emphasize the diagnostic and therapeutic challenges posed by this infection in immunocompromised or post-operative patients.
Main Methods:
- Case report detailing a six-month-old male child.
- Review of clinical presentation, diagnostic workup, and treatment course.
- Literature review on S. maltophilia meningitis in pediatric populations.
Main Results:
- The patient developed S. maltophilia meningitis post-neurosurgical procedure.
- Treatment was complicated by the bacterium's antibiotic resistance profile.
- Successful management required careful selection of antimicrobial agents.
Conclusions:
- S. maltophilia meningitis is a rare but critical complication in pediatric patients undergoing neurosurgery.
- Early recognition and appropriate, often multi-drug, antibiotic therapy are crucial for favorable outcomes.
- Further research is needed to establish optimal treatment guidelines for invasive S. maltophilia infections.
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