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Updated: Aug 9, 2026

Paradigms for Pharmacological Characterization of C. elegans Synaptic Transmission Mutants
Published on: August 18, 2008
Tonic immobility in chickens: possible involvement of monoamines
Abstract:
Tonic immobility in chickens was affected by a variety of drugs that act on monoaminergic systems. Compounds that enhanced the duration of tonic immobility were d-LSD, BOL-148, pargyline, and iproniazid; 5-hydroxytryptophan, p-CPA, and atropine had no effect. Injections of serotonin depressed response duration. A suggestive parallel was noted between the results of the present study and those of previous work reporting drug-induced suppression of raphe electrical activity. The data appear to implicate monoamines, especially serotonin, in the mediation of behavioral activation and suppression.
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