Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...

Chronic Kidney Disease III: Interprofessional Care

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...

Antihypertensive Drugs: Potassium-Sparing Diuretics

Antihypertensive Drugs: Potassium-Sparing Diuretics

Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the functional unit of the kidney. This heightened activity leads to increased sodium reabsorption and excessive excretion of potassium. To counteract this, potassium-sparing diuretics such as amiloride are used. They function by blocking these sodium channels, thereby reducing the influx of sodium into the epithelial cells and minimizing the loss of...

Chronic Kidney Disease IV: Nursing Management

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Sex, Head Size, and Male Mate Location Behavior Affect Allometric Scaling of the Eyes in <i>Centris pallida</i> (Hymenoptera: Apidae) Bees.

Integrative organismal biology (Oxford, England)·2026

Same author

Systematic review of the application of the Kidney Failure Risk Equation and Oxford classification in estimating prognosis in IgA Nephropathy.

Systematic reviews·2025

Same author

Bone flap infections after craniotomy: a review of 63 cases and the implications for definitions, classification and surveillance methodologies.

The Journal of hospital infection·2023

Same author

A decade of Clostridioides difficile infection: a constant challenge to maintain the status quo.

The Journal of hospital infection·2023

Same author

An actinometric method to characterize performance of reflecting UVC reactors used for water treatment.

Water research·2023

Same author

Antimicrobial overuse in COVID-19 - reasons to remain vigilant as we approach the winter 'twindemic'.

The Journal of hospital infection·2022

Search research articles

Related Experiment Video

Updated: May 7, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Management of hyperkalaemia.

A P Maxwell¹, K Linden, S O'Donnell

¹P Maxwell, Regional Nephrology Unit, Belfast City Hospital Belfast BT9 7AB, UK. a.p.maxwell@qub.ac.uk.

The Journal of the Royal College of Physicians of Edinburgh

|October 3, 2013

Summary

This summary is machine-generated.

Hyperkalaemia, high potassium levels, is a common hospital issue that can cause dangerous heart rhythms. Prompt treatment, often involving calcium and insulin, is crucial for patient safety and preventing cardiac complications.

Keywords:

Hyperkalaemia insulin and glucose infusion intravenous calcium salbutamol

Related Experiment Videos

Last Updated: May 7, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Area of Science:

Nephrology
Cardiology
Internal Medicine

Background:

Hyperkalaemia (elevated extracellular fluid potassium) is a frequent electrolyte disorder in hospitalized patients, affecting 1-10%.
While often asymptomatic, it can manifest as electrocardiogram (ECG) changes and lead to life-threatening cardiac arrhythmias.
Underlying causes typically involve impaired renal potassium excretion, particularly in the aldosterone-sensitive distal nephron.

Purpose of the Study:

To outline the recognition, risk management, and treatment of hyperkalaemia.
To highlight common etiologies and emphasize the importance of prompt intervention to prevent cardiac complications.

Main Methods:

Review of hyperkalaemia pathophysiology, focusing on renal potassium excretion.
Discussion of acute management strategies for life-threatening hyperkalaemia, including ECG monitoring.
Exploration of pharmacological interventions like intravenous calcium, insulin with glucose, and beta-2 agonists.

Main Results:

Prompt recognition and management of hyperkalaemia can prevent serious cardiac events.
Common causes include kidney failure, reduced distal nephron sodium delivery, and drugs affecting the renin-angiotensin-aldosterone system.
Treatment involves stabilizing cardiac membranes with calcium and lowering potassium via insulin/glucose and beta-2 agonists.

Conclusions:

Effective management of hyperkalaemia requires addressing underlying causes, reviewing medications, and implementing institutional protocols.
Improving patient safety for this common electrolyte disorder necessitates standardized prescribing and management approaches.