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Updated: May 7, 2026

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
Published on: August 16, 2021
Immunotherapy for pulmonary TB: antimicrobial peptides and their inducers
Cesar Enrique Rivas-Santiago1, Rogelio Hernández-Pando, Bruno Rivas-Santiago
1Rutgers University School of Public Health, Department of Environmental & Occupational Health, Center for Global Public Health, Piscataway, NJ, USA.
Abstract:
TB is an infectious disease that still has an enormous impact on public health worldwide. With the continuous increasing epidemic of multidrug-resistant TB, new drugs and vaccines are urgently needed. In the last decade there has been a broad advance in the knowledge of innate immunity in TB. Together with the growing research regarding immunomodulators, new promising insights have been developed that can contribute in the control of TB. This is the case of antimicrobial peptides, which can be potential therapeutic or adjuvant agents. The current high cost of antimicrobial peptide synthesis may be a current deterrent for treatment; antimicrobial peptide-inducers can be an alternative for low-cost treatment and/or adjuvants.
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