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Related Experiment Video

Updated: May 7, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

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Published on: February 26, 2013

Giant left atrial appendage: a rare anomaly.

Wilhelmina M M Kuiten¹, Linda M de Heer¹, Egidius E H L van Aarnhem¹

¹Department of Cardiothoracic Surgery, University Medical Centre Utrecht, The Netherlands.

The Annals of Thoracic Surgery

|October 4, 2013

Summary

Giant left atrial appendage, a rare congenital heart anomaly, can cause serious symptoms like stroke and shortness of breath. Surgical resection and pulmonary vein isolation effectively treated two such patients.

Keywords:

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Published on: April 24, 2017

Area of Science:

Cardiology
Congenital Heart Disease
Surgical Innovation

Background:

Giant left atrial appendage (GLAA) is an exceedingly rare congenital cardiac anomaly.
Few cases of GLAA have been documented in medical literature.
GLAA can be associated with significant clinical manifestations.

Observation:

Two patients presented with symptomatic GLAA.
One patient experienced atrial fibrillation with cerebellar infarct.
The other patient suffered from dyspnea attributed to GLAA.

Findings:

Both patients underwent successful surgical resection of the giant left atrial appendage.
Radiofrequency pulmonary vein isolation was performed concurrently in both cases.
Surgical intervention resolved the presenting symptoms.

Implications:

Early recognition of GLAA is crucial for effective management.
Surgical treatment, including appendage resection and pulmonary vein isolation, offers a viable therapeutic option.
This case series highlights the importance of considering rare pathologies in complex clinical presentations.