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Published on: July 27, 2022
Bone formation and osseointegration with titanium implant using granular- and block-type porous hydroxyapatite
Masahiko Minami1, Masaaki Takechi, Kouji Ohta
1Departments of Oral and Maxillofacial Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University.
Abstract:
The aim of the present study was to examine whether interconnected porous hydroxyapatite ceramics (IP-CHA) could be used as bone substitute for implant treatment in reconstructive surgery. We firstly assessed if surround of the titanium surface placed into granular or block-type IP-CHA can observe new bone formation in a rabbit bone defect model. Subsequently, osseointegration and stability of titanium implant inserted into block-type IP-CHA was investigated in a rabbit onlay graft model. Direct contact between new bone and the surface of the titanium in granular- or block-type IP-CHA was found in a rabbit bone defect. Further, new bone formation was found in direct contact with the implant surface in the block-type IP-CHA in an onlay graft model, and the implant stability quotient (ISQ) values were significantly increased after surgery. Therefore, IP-CHA may be a useful material for implant treatment in reconstructive surgery strategies.
