Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 7, 2026

A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents
08:02

A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents

Published on: July 16, 2020

Real-time atlas-based stereotactic neuronavigation.

Mark Vabulas1, Vinodh A Kumar, Jackson D Hamilton

  • 1*Anatom-e Information Systems, Ltd., Houston, Texas; ‡Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas; §Brainlab Inc, Westchester, Illinois; ‖Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Neurosurgery
|October 4, 2013
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hp1bp3 loss links chromatin reorganization to metabolic vulnerability in glioma.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Glo1 promotes glioma progression by modulating Sox2 transcriptional networks in glioma stem-like cells.

Neuro-oncology·2026
Same author

Cultured <i>ex vivo</i> human brain tissue maintains cell-type transcriptional identities.

Brain communications·2026
Same author

Reevaluating routine imaging: clinical utility of postoperative CT after stereotactic brain biopsy.

Journal of neurosurgery·2026
Same author

Seizure-presenting IDH-wildtype glioblastoma and the upregulation of a synaptic signature.

Journal of neurosurgery·2026
Same author

The global cancer crisis: a review of growing burden, deepening inequality and initiatives for prevention and early detection.

Ecancermedicalscience·2026
Same journal

Microsurgical Evacuation Efficacy and Functional Outcomes in Spontaneous Intracerebral Hemorrhage by Type of Antithrombotic Therapy.

Neurosurgery·2026
Same journal

Neurosurgeons Are Essential in the Interdisciplinary Care of Patients With Brain Metastasis.

Neurosurgery·2026
Same journal

Performance of Risk Scores in Predicting Intracranial Aneurysm Instability.

Neurosurgery·2026
Same journal

Electric-Scooters: An Emerging Source of High-Severity Pediatric Head Trauma.

Neurosurgery·2026
Same journal

Survival After Surgery for Spinal Osteosarcoma and the Role of Chemotherapy and Treatment Sequencing: A National Cohort Multivariable Analysis.

Neurosurgery·2026
Same journal

Safety and Efficacy of 3-Month Versus 6-Month Duration of Dual Antiplatelet Therapy in Pipeline Embolization Treatment of Intracranial Aneurysms.

Neurosurgery·2026
See all related articles

This study introduces interactive atlas-based navigation for brain tumor surgery, enhancing real-time anatomical and functional information during resection to improve patient outcomes.

Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Computational Anatomy

Background:

  • Eloquent brain tumor resection presents significant challenges in maximizing tumor removal while preserving neurological function.
  • Current neuronavigation systems require enhancement for real-time, integrated anatomical and functional guidance.

Purpose of the Study:

  • To develop and evaluate a software interface linking deformable anatomic templates (DATs) with intraoperative navigation systems.
  • To provide surgeons with real-time, patient-specific anatomical and functional information during tumor resection.

Main Methods:

  • Preoperative MRI, DTI, and fMRI were acquired for 3 patients undergoing tumor resection.
  • A deformable anatomic template (DAT) was registered to the neuronavigation system's coordinate space.

More Related Videos

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging
09:33

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging

Published on: November 15, 2024

Related Experiment Videos

Last Updated: May 7, 2026

A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents
08:02

A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents

Published on: July 16, 2020

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging
09:33

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging

Published on: November 15, 2024

  • The system provided real-time visualization of proximal structures and fused atlas imagery onto the patient's MRI.

    • Main Results:

    • Successful tumor resection was achieved in all 3 patients.
    • The DAT interface interactively visualized distances to critical anatomic and functional structures during surgery.
    • Real-time data guided the resection process, supplementing standard imaging modalities.

    Conclusions:

    • Interactive atlas-based navigation serves as a proof of concept for enhanced intraoperative guidance.
    • This approach provides detailed anatomical and functional insights beyond standard MRI, DTI, and fMRI.
    • The system can aid in direct electrical stimulation mapping and identifying critical structures to avoid during resection.