Intra-epithelial hyaline bodies in odontogenic cysts: an immunoperoxidase study

Fourteen dental cysts containing intra-epithelial hyaline bodies were stained for keratin, Factor VIII-related antigen, haemoglobin and fibrinogen using immunoperoxidase methods. Although the hyaline bodies were negative for all tested antigens fibrinogen was detected in the cores of some circular and polycyclic forms. These observations do not provide support for the proposed keratin, capillary endothelium or erythrocyte nature of these structures. The core staining for fibrinogen may support the theory that hyaline bodies are produced by a cellular reaction to extravasated serum.