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The impact of a community-based clinical trial educational intervention among underrepresented Chinese Americans

Grace X Ma1, Yin Tan, Natasha C Blakeney

  • 1Authors' Affiliations: Center for Asian Health, Department of Public Health, College of Health Professions, School of Medicine, Temple University; Asian Health Trilogy, Philadelphia, Pennsylvania; Education Network to Advance Cancer Clinical Trials (NACCT), Bethesda, Maryland; and Boston University School of Public Health, Boston, Massachusetts.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
|October 5, 2013
PubMed
Abstract

Insights

A community-based educational intervention significantly improved knowledge and intent to participate in cancer clinical trials among Chinese Americans. This approach is vital for increasing participation in cancer research among underrepresented populations.

Area of Science:

  • Oncology
  • Public Health
  • Health Disparities

Background:

  • Clinical trials are essential for advancing cancer prevention, diagnosis, and treatment.
  • Participation in clinical trials is notably low among racial/ethnic minority populations, especially Asian Americans.
  • Addressing this underrepresentation is crucial for equitable health innovation dissemination.

Purpose of the Study:

  • To develop and evaluate a culturally and linguistically appropriate, community-based educational intervention.
  • To increase knowledge of and intent to participate in cancer clinical trials among underrepresented Chinese Americans.

Main Methods:

  • A Community-Based Participatory Research approach guided intervention development and evaluation.
  • Community health educators (CHEs) were trained to deliver clinical trial education.
  • 247 eligible Chinese participants received the intervention, with pre- and post-tests administered.

Main Results:

  • Fifteen of 21 knowledge measures showed statistically significant improvement post-intervention (P < 0.05).
  • Education was the only demographic factor positively associated with increased clinical trial knowledge in multivariate analysis.

Conclusions:

  • Community-based interventions show promise for enhancing cancer clinical trial recruitment and participation among underrepresented Asian Americans.
  • Emphasizing benefits to both science and the broader Asian community is recommended for educational initiatives.
  • Improving clinical trial participation in the growing Asian American population is key to reducing health disparities.

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