Related Experiment Videos

Pachymeningitis in a young child responded to antitubercular therapy: a case report

Pradeep Kumar Sharma1, Bhaskar Saikia2, Rachna Sharma2

  • 1Pediatrics Intensive Care Unit, B. L. Kapur Super Speciality Hospital, New Delhi, India drsharma025@gmail.com.

Journal of Child Neurology
|October 5, 2013
PubMed

Insights

Pachymeningitis, a rare disease, typically affects adults. This report details the youngest pediatric case in India, who showed significant recovery with antitubercular therapy, suggesting its consideration for similar pediatric cases.

Area of Science:

  • Neurology
  • Pediatrics
  • Infectious Diseases

Background:

  • Pachymeningitis is a rare condition with varied causes, predominantly seen in adults.
  • Pediatric cases are exceptionally rare, with only four previously documented worldwide.

Observation:

  • This study presents the youngest reported pediatric patient diagnosed with pachymeningitis in India.
  • The patient exhibited hypertrophic pachymeningitis.

Findings:

  • The child demonstrated a remarkable response to antitubercular therapy.
  • Near-complete recovery was achieved following treatment.

Implications:

  • Antitubercular therapy should be considered for children in tuberculosis-endemic regions presenting with hypertrophic pachymeningitis.
  • This approach may prevent misdiagnosis as idiopathic hypertrophic pachymeningitis in pediatric patients.

Keywords:
antitubercular therapypachymeningitispediatric

Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...