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Related Experiment Video

Updated: May 7, 2026

A Unified Methodological Framework for Vestibular Schwannoma Research
08:43

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

Radiosurgery for vestibular schwannomas.

Jean Régis1, Romain Carron, Christine Delsanti

  • 1Department of Stereotaxic and Functional Neurosurgery, Gammaknife Unit, La Timone University Hospital, Inserm U751, 264, Rue Saint-Pierre 13385 Marseille Cedex 5, France.

Neurosurgery Clinics of North America
|October 8, 2013
PubMed
Summary

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Radiosurgery and stereotactic radiotherapy are effective and safe for managing vestibular schwannomas (VS). This approach, particularly for large tumors, preserves hearing while controlling tumor growth.

Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Audiology

Background:

  • Vestibular schwannomas (VS) are tumors affecting the cranial nerve responsible for hearing and balance.
  • Current management strategies for VS include observation, surgery, and radiotherapy.
  • Large VS pose significant treatment challenges, often leading to hearing loss and other neurological deficits.

Purpose of the Study:

  • To investigate the efficacy and safety of radiosurgery and stereotactic radiotherapy in managing vestibular schwannomas.
  • To evaluate a combined approach of partial microsurgical removal followed by radiosurgery for large Stage IV VS.
  • To assess the long-term outcomes, including hearing preservation, in a prospective cohort of VS patients treated with radiosurgery.

Main Methods:

  • Review of a unique prospective cohort of vestibular schwannoma patients.
Keywords:
Acoustic neuromasFacial palsyGamma KnifeHearingImbalanceRadiosurgeryTinnitus

Related Experiment Videos

Last Updated: May 7, 2026

A Unified Methodological Framework for Vestibular Schwannoma Research
08:43

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

  • Analysis of current literature on radiosurgery and stereotactic radiotherapy for VS.
  • Application of the Koos classification to stage tumors.
  • Prospective data collection on tumor control, neurological function, and hearing preservation.

    • Main Results:

    • Radiosurgery and stereotactic radiotherapy demonstrate high efficacy and safety in VS management.
    • A combined approach of partial microsurgery and radiosurgery is proposed for large Stage IV VS.
    • The authors' cohort shows a high rate of hearing preservation following radiosurgery for VS.
    • Long-term follow-up confirms the durability of tumor control and safety of the treatment.

    Conclusions:

    • Radiosurgery is a safe and effective treatment option for vestibular schwannomas.
    • The combined microsurgical and radiosurgical approach offers a promising strategy for large VS.
    • High rates of hearing preservation are achievable with radiosurgery, making it a valuable tool in VS management.