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10:07
Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages
Published on: June 23, 2013
The Semaphorin 3E/PlexinD1 axis regulates macrophage inflammation in obesity
Ann Marie Schmidt1, Kathryn J Moore
1Diabetes Research Program, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
Cell Metabolism
|October 8, 2013
Abstract:
Increased accumulation of adipose tissue macrophages in obesity propagates chronic inflammation that is closely associated with insulin resistance and type 2 diabetes. Semaphorin 3E, a guidance molecule for neurons, takes on a new role in obesity by directing the recruitment of macrophages in visceral adipose tissue (Shimizu et al., 2013).
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