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Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Published on: July 14, 2023

Diabetic autonomic neuropathy.

Aaron I Vinik¹, Tomris Erbas

¹Eastern Virginia Medical School, Strelitz Diabetes Center, Division of Endocrinology and Metabolism, Eastern Virginia Medical School, Norfolk, VA, USA.

Handbook of Clinical Neurology

|October 8, 2013

Summary

This summary is machine-generated.

Cardiac autonomic neuropathy (CAN) is a serious diabetes complication affecting heart rate and blood pressure. Early detection and treatment of autonomic imbalance can significantly reduce cardiovascular events and mortality in diabetic patients.

Keywords:

Sympathetic cardiovascular risk prediction central dopaminergic dysfunction imbalance parasympathetic potential for prevention and restoration of balance time and frequency domain analysis

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Area of Science:

Cardiology
Neurology
Endocrinology

Background:

Autonomic neuropathy, a complication of diabetes, affects numerous bodily functions due to the autonomic nervous system's widespread innervation.
Cardiac autonomic neuropathy (CAN) specifically impacts heart rate control and vascular dynamics, leading to various cardiovascular issues.
CAN is associated with increased risks of myocardial infarction, heart failure, and reduced survival rates in diabetic individuals.

Purpose of the Study:

To highlight the significance of autonomic neuropathy as a diabetes complication.
To discuss the clinical manifestations and risks associated with Cardiac Autonomic Neuropathy (CAN).
To emphasize the importance of early detection and management of autonomic dysfunction in diabetes.

Main Methods:

Review of existing literature and clinical studies on autonomic neuropathy and its cardiac manifestations.
Analysis of prevalence rates and associated risk factors for CAN.
Discussion of technological advancements for early identification of CAN using time and frequency domain analyses.

Main Results:

CAN prevalence varies widely (1-90%) and increases with age, diabetes duration, obesity, smoking, and poor glycemic control.
Autonomic imbalance may precede inflammatory processes in type 2 diabetes, with dopaminergic tone restoration reducing cardiovascular events by nearly 50%.
CAN is linked to resting tachycardia, postural hypotension, exercise intolerance, and increased cardiovascular lability.

Conclusions:

Autonomic dysfunction, particularly CAN, is a critical and often underrecognized complication of diabetes.
Early objective identification of CAN is possible with advanced measurement techniques.
Managing autonomic imbalance, potentially through restoring dopaminergic tone, offers a significant therapeutic target to reduce cardiovascular morbidity and mortality in diabetes.