Related Experiment Video
Updated: May 7, 2026
Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads
Published on: June 28, 2024
A nanosensor based on quantum-dot haptens for rapid, on-site immunoassay of cyanotoxin in environmental water
Long Feng1, Anna Zhu, Hongchen Wang
1School of Environment and Natural Resources, Renmin University of China, Haidian, Beijing 100872, China; School of Environment, Tsinghua University, Haidian, Beijing 100084, China.
Abstract:
A nanoprobe based on quantum-dot (QD) haptens was synthesized by conjugating carboxyl quantum dots with aminoethyl-microcystin (MC)-leucine-arginine (LR). A two-alkyl group was introduced to supply a spacer between the QD nanoprobe and anti-MC-LR antibody to reduce the steric hindrances of immunoreaction. The sensor system based on a portable optofluidic platform exhibited a liner range of 0.10-4.0 µg/L for MC-LR with a detection limit of 0.03 µg/L. The proposed sensor has potential application in the rapid, on-site detection of MC-LR in real water samples.
