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Ligand Binding Sites

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...

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Related Experiment Video

Updated: May 7, 2026

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Published on: October 15, 2018

Using molecular dynamics to elucidate the structural basis for function in pLGICs

Myles H Akabas¹

¹Departments of Physiology and Biophysics, Neuroscience, and Medicine, Albert Einstein College of Medicine, Bronx, NY 10461.

Proceedings of the National Academy of Sciences of the United States of America

|October 8, 2013

Summary

No abstract available in PubMed .

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