Greater saphenous venous access as an alternative in children
Related Experiment Video
Updated: May 7, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
David J Aria1, Seth Vatsky, Robin Kaye
1Department of Radiology, Phoenix Children's Hospital, 1919 E. Thomas Road, Phoenix, AZ, 85012, USA, daria@phoenixchildrens.com.
Insights
The greater saphenous vein is a safe and effective alternative for placing central venous catheters in children, especially those under 10 kg. This approach offers a viable option for difficult venous access in pediatric patients.
Area of Science:
- Pediatric Interventional Radiology
- Vascular Access Procedures
- Neonatal and Pediatric Critical Care
Background:
- Obtaining venous access in high-risk pediatric patients, including neonates and children under 10 kg, presents significant challenges.
- The greater saphenous vein has been underutilized as a primary venous access site in pediatric interventional radiology.
Purpose of the Study:
- To evaluate the effectiveness and safety of using the greater saphenous vein for peripherally inserted central catheter (PICC) placement in children.
- To establish the greater saphenous vein as a suitable alternative for venous access in challenging pediatric cases.
Main Methods:
- Retrospective analysis of 86 pediatric patients (3 days to 17 years) undergoing PICC placement via the greater saphenous vein.
- Procedures performed by interventional radiologists using ultrasound guidance or anatomical landmarks.
- Data collected on patient demographics, indications for access, procedural success, and complications.
Main Results:
- Successful PICC placement was achieved in 67 out of 86 patients (78%), with 51% weighing less than 10 kg.
- Mean vessel diameter was larger in successful placements (1.83 mm) compared to failures (1.35 mm).
- No insertion-related complications were noted, and a total of 1,060 catheter days were reviewed without mechanical or infectious complications.
Conclusions:
- The greater saphenous vein is a safe and effective alternative for venous access in pediatric patients, particularly those under 10 kg.
- This approach can preserve future venous access sites and is beneficial for select older children who are not mobile.
- Greater saphenous vein access may be a preferred initial site in small children requiring central venous catheters.
Background:
In the pediatric population, obtaining venous access in high-risk neonates, severely ill children with cardiac anomalies or very young children (<10 kg) can be very challenging. In the literature to date, the greater saphenous vein has not been primarily used by interventional radiologists as an entry site for venous access in children.
Objective:
To demonstrate the utility and effectiveness of using the greater saphenous vein as a venous access site for the placement of peripherally inserted central catheters in children.
Materials And Methods:
This is a retrospective study from a large tertiary care children's hospital from November 2010 to August 2012. Peripheral insertion of central venous catheters (PICC) using the greater saphenous vein was attempted in 86 children ranging in age from 3 days to 17 years (mean: 1.8 years). Indications included congenital heart disease, urinary tract infection, intravenous access, pneumonia, meningitis, total parenteral nutrition, sepsis and other infections. All procedures were performed by interventional radiologists. No insertion-related complications were identified. There was no follow-up planning, but no mechanical or infectious complications were brought to our attention.
Results:
Of the 86 patients in whom PICC placement was attempted, placement was successful in 67 (78%). Forty-two PICCs were placed in the greater saphenous vein at the thigh level using US guidance and 25 at the ankle level using anatomical landmarks. The mean weight of the 67 patients who underwent successful placement was 9.98 kg, with 51 (76%) weighing <10 kg. The mean vessel diameter in placement failures was 1.35 mm compared to 1.83 mm in successful placement. Inability to obtain venous access was the cause of failure in all thigh access sites while inability to advance the catheter centrally was the cause of failure for all ankle access sites. A total of 1,060 catheter days (with a maximum dwell time of 97 days in one patient) were reviewed without complication.
Conclusion:
In children, the greater saphenous vein provides a safe, suitable alternative for venous access, particularly in very young children (<10 kg) and in a select group of older children who are not mobile. In the lower extremities, greater saphenous venous puncture and access may be a preferred initial access site in small children to preserve future venous access.
More Related Videos
Related Concept Videos
Veins of Lower Limbs
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the knee,...
Hemodialysis I: Introduction
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Pulse Assessment Sites
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Varicose Veins II: Diagnostic Studies and Interprofessional Care

