Genetic testing in children
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Updated: May 7, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
1Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India. Correspondence to: Dr Shubha Rajendra Phadke, Head of the Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rai Bareilley Road, Lucknow 226 001, Uttar Pradesh, India. shubharaophadke@gmail.com.
Abstract:
Increasing availability of DNA based tests in clinical practice has lead to widespread debate on the ethical issues involved. The wider usage of these tests in children has raised many questions regarding the ethics, validity of the request and its effects on childs psychosocial well-being. Though there have been much discussion with many studies attempting to address the issue, there is no consensus. Formulation of guidelines has been hampered by the diversity of tests available for varied indications and lack of research studying the effects of testing in children over a time. Some tests have valid indications with proven benefits over harms while others have less clear justification. We attempt to address this issue with the intent to sensitize the caregivers regarding various aspects to be considered before offering any genetic tests in children.
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