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Genetic Screens02:46

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Genetic testing in children.

Shubha Phadke1, Mamatha Gowda

  • 1Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India. Correspondence to: Dr Shubha Rajendra Phadke, Head of the Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rai Bareilley Road, Lucknow 226 001, Uttar Pradesh, India. shubharaophadke@gmail.com.

Indian Pediatrics
|October 8, 2013
PubMed
Summary

Genetic testing in children raises ethical questions about psychosocial well-being, with no current consensus on guidelines. Caregivers need sensitization to the various aspects before offering genetic tests to children.

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Area of Science:

  • Medical Ethics
  • Pediatric Genetics
  • Clinical Diagnostics

Background:

  • The increasing availability of DNA-based tests in clinical practice has sparked ethical debates.
  • Widespread use of genetic tests in children raises concerns about ethics, request validity, and psychosocial impact.

Purpose of the Study:

  • To address the ethical considerations surrounding genetic testing in children.
  • To sensitize caregivers about factors to consider before offering genetic tests to pediatric patients.

Main Methods:

  • Review of existing literature and ethical discussions on genetic testing in children.
  • Analysis of the diversity of available genetic tests and their indications.
  • Examination of the lack of longitudinal research on the effects of genetic testing in children.

Main Results:

  • There is a lack of consensus on the ethical guidelines for genetic testing in children.
  • Some genetic tests have clear indications and proven benefits, while others have less defined justifications.
  • The impact of genetic testing on a child's psychosocial well-being remains a significant concern.

Conclusions:

  • Further research is needed to establish clear guidelines for genetic testing in children.
  • Caregivers require comprehensive information to make informed decisions about genetic testing for children.
  • Balancing the benefits and harms of genetic testing is crucial for pediatric patient welfare.