Related Experiment Video
Updated: May 7, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
Amino-[(1H-benzimidazol-2-yl)amino]-methaniminium 4-methyl-benzene-sulfonate
Shaaban K Mohamed1, Mehmet Akkurt, Mahmoud A A Elremaily
1Chemistry and Environmental Division, Manchester Metropolitan University, Manchester M1 5GD, England ; Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt.
Abstract:
The asymmetric unit of the title salt, C8H10N5 (+)·C7H7O3S(-), consists of two amino-[(1H-benzimidazol-2-yl)amino]-meth-an-im-inium cations and two 4-methyl-benzene-sulfonate anions. The cations are each stabilized by intra-molecular N-H⋯N hydrogen bonds between the free amino groups and the imine N atoms of the benzimidazole units, forming S(6) ring motifs. In the crystal, cations and anions are linked by N-H⋯O and C-H⋯O hydrogen bonds, forming a three-dimensional supra-molecular framework. Two strong π-π stacking inter-actions [centroid-centroid distances = 3.4112 (14) and 3.4104 (14) Å] also occur between the centroids of the imidazole rings of like cations.
More Related Videos
Related Concept Videos
Structure of Amines
Electrophilic Aromatic Substitution: Sulfonation of Benzene
Amines to Sulfonamides: The Hinsberg Test
Generally, a primary amine reacts with the Hinsberg reagent to produce an N-substituted benzenesulfonamide. The electron-withdrawing sulfonyl...
Mass Spectrometry of Amines
Basicity of Heterocyclic Aromatic Amines
Basicity of Aromatic Amines

