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Updated: May 7, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
4,6-Di-tert-butyl-2,3-di-hydroxy-benzalde-hyde
Max Arsenyev1, Eugene Baranov, Sergey Chesnokov
1Laboratory of Free Radical Polymerization, G.A. Razuvaev Institute of -Organometallic Chemistry of the Russian Academy of Science, Tropinina str, 49, Nizhny Novgorod, 603950, Russian Federation.
Abstract:
The title compound, C15H22O3, crystallizes with two independent mol-ecules in the asymmetric unit. In each mol-ecule, one hy-droxy group (at position 2) is involved in an intra-molecular O-H⋯O hydrogen bond, and another one (at position 3) exhibits bifurcated hydrogen-bonding being involved in intra- and inter-molecular O-H⋯O inter-actions. In the crystal, O-H⋯O hydrogen bonds link alternating independent mol-ecules into chains running along [010].
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