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A near-infrared dye based on BODIPY for tracking morphology changes in mitochondria
Na Jiang1, Jiangli Fan, Tao Liu
1State Key Laboratory of Fine Chemicals, Dalian University of Technology, No. 2 Linggong Road, High-Tech District, Dalian 116024, China. fanjl@dlut.edu.cn pengxj@dlut.edu.cn.
Chemical Communications (Cambridge, England)
|October 8, 2013
Abstract:
M-DPT, a BODIPY-based water soluble near-infrared fluorescent probe with thiophene at the 1,7-position, is synthesized. M-DPT is found to possess high specificity to mitochondria, superior photostability, and appreciable tolerance to microenvironmental changes. Thus, this probe is a highly suitable imaging agent for targeting mitochondria and tracking morphology changes.
