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Updated: May 7, 2026

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
Published on: November 7, 2020
Hepatotoxicity and drug interactions in liver transplant candidates and recipients
Neehar D Parikh1, Josh Levitsky
1Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, NMH/Arkes Family Pavilion 19th Floor, 676 North Saint Clair Street, Suite 1900, Chicago IL 60611, USA.
Abstract:
In this article the medications that have been shown to increase rates of drug-induced liver injury in patients with cirrhosis and the important drug-drug interactions in recipients of liver transplantation are reviewed. In general, the risk of drug-induced liver injury in patients with cirrhosis does not seem to be higher when compared with the noncirrhotic population. There are, however, 2 classes of agents that have been implicated-medications used to treat tuberculosis and medications used to treat human immunodeficiency virus infection. However, with careful monitoring, even significant interactions can be effectively managed.
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