Related Experiment Video
Updated: May 7, 2026

09:25
Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
19.1K
Primary osteosarcoma of clivus: a short report
Sandeep Mohindra1, Amey Savardekar, Shantanam S Mahalingam
1Department of Neurosurgery, Postgraduate Institute of Medical Education and Research , Chandigarh , India.
British Journal of Neurosurgery
|October 9, 2013
Summary
Osteosarcoma, a rare bone cancer, can affect the skull base. This report details a case of clival osteosarcoma in a 55-year-old male, covering diagnosis, treatment, and patient outcome.
Area of Science:
- Oncology
- Skeletal Neoplasms
- Skull Base Tumors
Background:
- Osteosarcoma is the second most common primary malignant skeletal neoplasm after multiple myeloma.
- It is characterized by aggressive behavior and the production of osteoid by malignant spindle cells.
- Calvarial involvement is a rare presentation of osteosarcoma.
Observation:
- A case study of a 55-year-old male patient with clival osteosarcoma is presented.
- The report includes detailed clinical presentation and radiological findings.
- Management strategies and patient outcomes are documented.
Findings:
- Clival osteosarcoma, though rare, represents a significant diagnostic and therapeutic challenge.
- The study highlights the importance of thorough radiological evaluation for accurate diagnosis.
- Successful management and outcome depend on a multidisciplinary approach.
Implications:
- This case contributes to the limited literature on clival osteosarcoma, enhancing understanding of this rare entity.
- Findings may inform clinical decision-making for similar rare skull base tumors.
- Further research into optimal treatment protocols for cranial osteosarcomas is warranted.
Related Concept Videos
Sutures of the Skull
13.9K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
13.9K
Changes in the Appendicular Skeleton with Age
3.2K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.2K

