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Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
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Visceral larva migrans presenting as multiple liver abscesses.

Jeyamani Ramachandran1, Anuradha Chandramohan, Sajith Kattiparambil Gangadharan

  • 1Professor and Head, Department of Hepatology, Christian Medical College Hospital, Vellore, Tamilnadu 632004, India. jeyapati@yahoo.com.

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|October 9, 2013
PubMed
Summary

Visceral larva migrans (VLM), caused by dog and cat roundworm larvae, can manifest as rare liver abscesses. Diagnosis involves eosinophilia and imaging, with successful treatment using anthelmintics.

Keywords:
Visceral larva migransanthelminticseosinophiliagranulomasliver abscesses

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Area of Science:

  • Hepatology
  • Parasitology
  • Infectious Diseases

Background:

  • Visceral larva migrans (VLM) is a rare parasitic infection caused by ascarid worm larvae from dogs and cats.
  • VLM can present as eosinophilic necrotizing granulomas in the liver, mimicking liver abscesses.

Purpose of the Study:

  • To report two cases of visceral larva migrans presenting with liver abscesses.
  • To highlight diagnostic features and treatment outcomes for VLM in the liver.

Main Methods:

  • Case report of two patients with prolonged fever and abdominal pain.
  • Diagnostic workup included peripheral blood eosinophil counts, liver imaging (ultrasound/CT), and liver biopsy.
  • Treatment involved repeated courses of combination anthelmintics.

Main Results:

  • Both patients presented with high-grade fever and abdominal pain for 3-4 months.
  • Key findings included marked peripheral eosinophilia, multiple liver lesions with migratory tracts, and necrotizing eosinophilic granulomas on biopsy.
  • Complete recovery was achieved with anthelmintic therapy.

Conclusions:

  • Visceral larva migrans is a rare but treatable cause of liver abscesses.
  • Early diagnosis based on clinical presentation, eosinophilia, imaging, and biopsy is crucial.
  • Combination anthelmintic therapy is effective for treating hepatic VLM.