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Published on: July 27, 2018
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Geminiviruses: masters at redirecting and reprogramming plant processes
Linda Hanley-Bowdoin1, Eduardo R Bejarano, Dominique Robertson
1Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina 27695-7622, USA.
Nature Reviews. Microbiology
|October 9, 2013
Summary
Geminiviruses, a major plant virus family, utilize small DNA genomes to reprogram host cells. This review details how these viruses manipulate plant processes for infection, impacting cell cycle, defense, and signaling.
Area of Science:
- Plant virology
- Molecular plant-pathogen interactions
Background:
- Geminiviridae is a large and significant family of plant viruses.
- Geminiviruses possess small, single-stranded DNA genomes encoding 5-7 proteins.
Purpose of the Study:
- To review current knowledge on geminivirus-plant host interactions.
- To describe the functional consequences of these interactions during infection.
Main Methods:
- Literature review of geminivirus research.
- Analysis of molecular mechanisms underlying host-pathogen interactions.
Main Results:
- Geminivirus proteins redirect host machinery for infection.
- Interactions involve reprogramming cell cycle and transcriptional controls.
- Viruses inhibit cell death, interfere with signaling, and suppress plant defenses.
Conclusions:
- Geminiviruses extensively manipulate host processes for successful infection.
- Understanding these interactions is crucial for developing antiviral strategies.
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