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Related Experiment Video

Updated: May 7, 2026

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
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Drug-induced uveitis.

Ramana S Moorthy1, Nikolas J S London, Sunir J Garg

  • 1aAssociated Vitreoretinal and Uveitis Consultants bEugene and Marilyn Glick Eye Institute and Department of Ophthalmology, Indiana University Medical Center cSt. Vincent Hospital and Health Services, Indianapolis, Indiana dRetina Consultants San Diego, La Jolla, California eMidAtlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania fDepartment of Ophthalmology, California Pacific Medical Center, San Francisco gThe Department of Ophthalmology, Stanford University School of Medicine, Stanford hWest Coast Retina Medical Group, San Francisco, California, USA.

Current Opinion in Ophthalmology
|October 9, 2013
PubMed
Summary
This summary is machine-generated.

Certain medications can cause ocular inflammation, leading to drug-induced uveitis. Identifying these drugs is crucial for effective management and improved visual outcomes in patients.

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Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Over 50% of uveitis cases lack identifiable causes.
  • Drug-induced ocular inflammation is an increasing concern with new medications.
  • Common culprits include bisphosphonates, biologics, and intravitreal injections.

Purpose of the Study:

  • To review known and emerging drug associations with uveitis.
  • To categorize the strength of drug-uveitis associations.
  • To highlight the importance of medication history in diagnosis and management.

Main Methods:

  • Review of literature on drug-induced uveitis.
  • Emphasis on new medication associations.
  • Utilizing Naranjo's criteria to classify drug-uveitis relationships.

Main Results:

  • Several systemic, intraocular, and topical medications are linked to uveitis.
  • Newer agents like biologics and anti-VEGF drugs are increasingly implicated.
  • Drug-induced uveitis is often overlooked but readily treatable.

Conclusions:

  • Drug-induced uveitis is a significant and growing clinical issue.
  • A thorough patient history is key to identifying causative agents.
  • Discontinuation of the offending drug and standard therapy often leads to prompt recovery.