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Updated: May 7, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Ischemic mitral regurgitation: current trends and treatment
Elsayed Elmistekawy1, Thierry Mesana, Vincent Chan
1Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Severe ischemic mitral regurgitation (MR) in coronary artery disease patients requires surgical intervention. Advances in repair and percutaneous therapies offer new hope for improved outcomes and treatment options.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Background:
- Ischemic mitral regurgitation (MR) is a frequent complication in patients with coronary artery disease (CAD).
- Understanding the specific mechanisms of MR is crucial for effective treatment strategies.
Purpose of the Study:
- To review current literature on the treatment of ischemic mitral regurgitation.
- To highlight recent advancements and therapeutic options for ischemic MR.
Main Methods:
- Literature review of recent publications on ischemic mitral regurgitation treatment.
- Analysis of outcomes based on regurgitation mechanism and therapeutic approach.
Main Results:
- New therapies including remodeling rings and percutaneous approaches have emerged.
- Insights into mitral valve replacement have advanced treatment protocols.
- Outcomes are increasingly described based on specific regurgitation mechanisms.
Conclusions:
- Mitral valve surgery with coronary artery bypass grafting is the most effective treatment for severe symptomatic ischemic MR.
- Patient survival with ischemic MR remains poor, necessitating further therapeutic advancements.
- Mitral valve repair may enhance long-term surgical durability; percutaneous therapies are emerging options for non-surgical candidates.
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