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![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Phenol ring nitration induced by the unprecedented reduction of the Cu(II) centre by nitrogen dioxide
Abstract:
Nitrogen dioxide (˙NO2) induces tyrosine nitration through a radical mechanism in biological systems. Two copper(II) complexes, 1 and 2, with ligands L₁ and L₂ [L₁ = 2,4-di-tert-butyl-6-(((2-(dimethylamino)ethyl)(isopropyl)amino)methyl)phenol; L₂ = 6,6'-(((2-(dimethylamino)ethyl)azanediyl)bis(methylene))bis(2,4-di-tert-butylphenol)], respectively, have been made to react with ˙NO2. In both cases, the reduction of the copper(II) center was observed in the presence of ˙NO2 which induces phenol ring nitration through nitronium ion (NO2(+)) formation.
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