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Therapeutically reeducating macrophages to treat GBM
Christopher Garris1, Mikael J Pittet
11] Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Graduate Program in Immunology, Harvard Medical School, Boston, Massachusetts, USA.
Nature Medicine
|October 9, 2013
Abstract:
Glioblastoma multiforme (GBM) is the most common type of aggressive malignant brain cancer. The current lack of successful therapeutics means that this disease has a dismal prognosis. However, a new study in mice offers hope for patients with GBM by demonstrating the efficacy of a novel drug that targets GBM-associated macrophages (pages 1264–1272).
