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Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Malignant pleural mesothelioma: current and future perspectives
Konstantinos Porpodis1, Paul Zarogoulidis, Efimia Boutsikou
1Pulmonary Department-Oncology Unit, "G. Papanikolaou" General Hospital, Aristotle Univesrity of Thessaloniki, Thessaloniki, Greece;
Abstract:
Mesothelioma still remains an occupational related cancer with severe outcome. It is usually diagnosed at advanced stage since it does not demonstrate early symptoms. Several efforts have been made towards removing all materials inducing mesothelioma in the work setting and new work protection measures have been applied. Although we have new targeted treatments and radical surgery as arrows in the quiver, the type of mesothelioma and early diagnosis still remain the best treatment approach. Novel treatment modalities have been explored and several others are already on the way. In the current review we will present current data for mesothelioma and future perspectives.
Insights
Mesothelioma is an occupational cancer often diagnosed late. Early detection and understanding mesothelioma types remain key to effective treatment, despite advances in therapies.
Area of Science:
- Oncology
- Occupational Health
Background:
- Mesothelioma is a severe occupational cancer.
- Diagnosis is often delayed due to a lack of early symptoms.
- Despite advancements, mesothelioma remains challenging to treat effectively.
Purpose of the Study:
- To review current data on mesothelioma.
- To discuss future perspectives in mesothelioma research and treatment.
Main Methods:
- Review of current scientific literature on mesothelioma.
- Analysis of existing and emerging treatment strategies.
Main Results:
- Mesothelioma is strongly linked to occupational exposures.
- Early diagnosis and mesothelioma type are critical for treatment success.
- Novel treatments are under investigation.
Conclusions:
- Improving early diagnosis is crucial for better mesothelioma outcomes.
- Continued research into novel treatment modalities is essential.
- Workplace safety measures are vital for prevention.
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