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Sample Handling

Sample Handling

Transportation of samples from the collection point to the laboratory, as well as storage and preservation techniques, are crucial for maintaining sample integrity and ensuring accurate and reliable test results.
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...

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Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

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Published on: November 30, 2022

Commercially available blood storage containers.

C V Prowse¹, D de Korte, J R Hess

¹University of Edinburgh, Edinburgh, UK.

|October 10, 2013

Summary

This summary is machine-generated.

Plastic blood bags enhance blood safety and storage. While DEHP-free options exist for platelets, challenges remain for red blood cell and plasma storage, necessitating further research.

Keywords:

biocompatibility blood storage containers di-2-ethylhexyl phthalate plasticizers polyvinyl chloride

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Area of Science:

Biomaterials Science
Transfusion Medicine
Polymer Chemistry

Background:

Plastic blood bags are crucial for safe blood component separation and storage.
Advancements are driven by medical, scientific, business, and environmental factors.
Material limitations, consumer acceptance, and regulatory hurdles impact progress.

Purpose of the Study:

To evaluate current plastic blood bag products based on manufacturer submissions.
To assess how effectively products address scientific challenges in blood storage.
To identify specific issues related to plasticizers, bag dimensions, and material properties.

Main Methods:

Manufacturers submitted lists of blood bags.
Lists were combined, sorted by planned use, and analyzed by experts.
Specific issues like DEHP in PVC bags, platelet bag specifications, and plasma bag fracture resistance were examined.

Main Results:

DEHP-free, PVC-free platelet bags with improved gas diffusion are available.
Alternatives for plasma storage with better low-temperature fracture resistance exist.
Most red blood cell storage still relies on DEHP-plasticized PVC due to lack of satisfactory alternatives.

Conclusions:

Optimal alternatives for red blood cell storage in plastic bags are still under development.
The significance of various alternative platelet storage systems requires further understanding.
The necessity of removing DEHP from blood bags remains to be definitively determined.