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Different effects of local anesthetics on calcium influx into rat mast cells
General Pharmacology
|January 1, 1985
Abstract:
Lidocaine, W49091, procaine and benzocaine inhibited mast cell secretion induced by concanavalin A and A23187. They inhibited Ca influx stimulated by concanavalin A, suggesting that they inactivate Ca channel of mast cells. Lidocaine and procaine inhibited Ca influx stimulated by A23187, but W49091 and benzocaine did not.