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Prevalence of minor depression in elderly persons with and without mild cognitive impairment: a systematic review

M Polyakova1, N Sonnabend, C Sander

  • 1Department of Psychiatry, University of Leipzig, Leipzig, Germany; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, Germany; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.

Journal of Affective Disorders
|October 10, 2013
PubMed
Abstract

Insights

Minor depression (MinD) is common in older adults, affecting nearly 20% of those with mild cognitive impairment (MCI). Further research is needed to understand the prevalence of MCI in MinD patients.

Area of Science:

  • Gerontology
  • Psychiatry
  • Neurology

Background:

  • Minor depression (MinD) and mild cognitive impairment (MCI) are prevalent conditions in older adults, frequently co-occurring.
  • Understanding the prevalence of MinD in elderly individuals with and without MCI is crucial for effective healthcare management.

Purpose of the Study:

  • To review and present the prevalence rates of minor depression in older patients, both with and without mild cognitive impairment.
  • To identify risk factors, comorbidities, and healthcare utilization associated with minor depression in the elderly population.

Main Methods:

  • Systematic review of electronic databases (Medline, ISI Web of Knowledge, Psycinfo, Cochrane).
  • Inclusion criteria: individuals aged 55+, diagnosed with MinD per DSM criteria.
  • Data extraction focused on prevalence, risk factors, comorbidity, and healthcare usage.

Main Results:

  • Point prevalence of MinD is higher in medical settings (median 14.4%) compared to community (10.4%) and primary care (7.7%).
  • Approximately 20% of elderly patients with MCI exhibit symptoms of MinD.
  • Risk factors for MinD include female gender, cerebrovascular disease history, anxiety, loneliness, and institutional care.

Conclusions:

  • Methodological variations across studies contribute to a wide range of reported prevalence rates.
  • Insufficient evidence exists regarding the prevalence of MCI in individuals with MinD.
  • Future longitudinal studies using structured interviews are recommended to distinguish late-life depression from MCI or early Alzheimer's disease.
Keywords:
ElderlyLate lifeMCIMild cognitive impairmentMinor depression

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