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Updated: May 7, 2026

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
[Brain protection during operation for aortic arch aneurysms].
Koichi Adachi1, Atsushi Yamaguchi, Koichi Yuri
1Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Aortic arch replacement using antegrade selective cerebral perfusion is safe, but requires precise imaging to avoid neurological deficits. Atheroembolism from diseased aortas remains a challenge.
Area of Science:
- Cardiovascular Surgery
- Neurological Protection
- Vascular Imaging
Context:
- Aortic arch replacement is a complex procedure requiring meticulous surgical technique.
- Moderate hypothermic circulatory arrest and antegrade selective cerebral perfusion are standard methods.
- Preventing permanent neurological deficit is a primary concern in aortic arch surgery.
Purpose:
- To evaluate the safety and efficacy of moderate hypothermic circulatory arrest with antegrade selective cerebral perfusion for aortic arch replacement.
- To identify key factors for preventing neurological complications during the procedure.
- To assess the outcomes of aortic arch replacement in a large patient cohort.
Summary:
- A comprehensive pre-operative evaluation including computed tomography (CT), magnetic resonance imaging (MRI), and intraoperative epiaortic echography is crucial for safe cannulation and cerebral perfusion.
- Surgical techniques emphasizing good exposure, irrigation, and flushing of atheromatous debris are vital.
- In a series of 410 aortic arch replacements (1991-2013), overall mortality was 5.4% and stroke rate was 2.4%, with higher rates in emergency cases.
- Antegrade selective cerebral perfusion facilitates secure distal anastomosis but atheroembolism from a "shaggy" aorta persists as an unresolved issue.
Impact:
- This study highlights the importance of advanced imaging and meticulous surgical technique in reducing neurological complications during aortic arch replacement.
- The findings underscore the effectiveness of antegrade selective cerebral perfusion in protecting the brain and enabling complex aortic reconstructions.
- Further research is needed to address the challenge of atheroembolism in patients with atherosclerotic aortas undergoing arch surgery.
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