A turn-on indole-based sensor for hydrogen sulfate ion
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Updated: May 7, 2026

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
Published on: June 27, 2022
Chin-Feng Wan1, Shih-Tse Yang, Hsiang-Yi Lin
1School of Applied Chemistry, Chung Shan Medical University, Taichung City, 40201, Taiwan.
Abstract:
A simple indole-based receptor 1 was prepared by a simple Schiff-base reaction of 1H-indole-3-carbaldehyde with ethane 1,2-diamine and its fluoroionophoric properties toward anions were investigated. Indole-based receptor 1 acts as a selective turn-on fluorescent sensor for HSO4(-) in methanol among a series of tested anions. Fluorescence spectroscopy, ultraviolet and nuclear magnetic resonance imaging support that the HSO4(-) indeed interacted with imine nitrogen and the proton of nitrogen in indole ring.
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