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Updated: May 7, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
Published on: July 26, 2017
Targeted theranostic nanoparticles: receptor-mediated entry into cells, pH-induced signal generation and cytosolic
Ji Yeon Lee1, Doo-Yeol Choi, Mi Young Cho
1Graduate School and Department of Analytical Science and Technology, Chungnam National University, Daejeon, 305-764, Republic of Korea.
Abstract:
Virus-like theranostic nanoparticles: virus-like poly(amino acid) nanoparticles are synthesized that can be internalized via receptor-mediated endocytosis, resulting in encapsulated pH-activatable fluorescence probes that can be turned on in acidic environments but otherwise remain undetectable. The encapsulated anticancer drugs are also released into cytosol by endosome disruption.
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