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Updated: May 7, 2026

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Published on: January 22, 2018
Chest wall sarcoma: 18F-FDG PET/CT in a patient with Li-Fraumeni syndrome
Tyson Chadaz1, Susan K Hobbs, Hongju Son
1From the Department of Imaging Sciences, University of Rochester Medical Center, Rochester, NY.
Abstract:
Li-Fraumeni syndrome is an autosomal dominant inherited disorder also known as the SBLA cancer syndrome (sarcoma, breast, leukemia, and adrenal). A 39-year-old female patient with a history of bilateral breast cancer treated with bilateral mastectomies and radiation treatment 4 years ago and left chest wall pleomorphic sarcoma 1 year ago presented with a small hypermetabolic right chest wall mass on 18F-FDG PET/CT. This mass was found to be a spindle cell sarcoma. FDG PET/CT plays an important role in following up oncology patients, particularly in group of high-risk malignancy, for detecting small hypermetabolic lesions.
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