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Updated: May 7, 2026

Hydrolysis of a Ni-Schiff-Base Complex Using Conditions Suitable for Retention of Acid-labile Protecting Groups
Published on: April 6, 2017
Schiff bases: a short survey on an evergreen chemistry tool
Wenling Qin1, Sha Long, Mauro Panunzio
1Dipartimento di Chimica "G. Ciamician" Via Selmi 2, Bologna 40126, Italy. mauro.panunzio@unibo.it.
Abstract:
The review reports a short biography of the Italian naturalized chemist Hugo Schiff and an outline on the synthesis and use of his most popular discovery: the imines, very well known and popular as Schiff Bases. Recent developments on their "metallo-imines" variants have been described. The applications of Schiff bases in organic synthesis as partner in Staudinger and hetero Diels-Alder reactions, as "privileged" ligands in the organometallic complexes and as biological active Schiff intermediates/targets have been reported as well.
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