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Updated: May 7, 2026

Author Spotlight: Collecting Neural Stem and Progenitor Cells from Live Animals Using a Novel Brain Milking Protocol
Published on: February 9, 2024
Neural stem cells harvested from live brains by antibody-conjugated magnetic nanoparticles
C N P Lui1, Y P Tsui, A S L Ho
1Department of Biology, Hong Kong Baptist University, Kowloon Tong, Hong Kong (China).
Abstract:
It stems from the magnetism: The extraction of stem/progenitor cells from the brain of live animals is possible using antibodies conjugated to magnetic nanoparticles (Ab-MNPs). The Ab-MNPs are introduced to a rat's brain with a superfine micro-syringe. The stem cells attach to the Ab-MNPs and are magnetically isolated and removed. They can develop into neurospheres and differentiate into different types of cells outside the subject body. The rat remains alive and healthy.
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