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Published on: December 6, 2016
Obstructive sleep apnea in children: a critical update
Hui-Leng Tan1, David Gozal, Leila Kheirandish-Gozal
1Sections of Pediatric Sleep Medicine and Pediatric Pulmonology, Department of Pediatrics, Comer Children's Hospital, Pritzker School of Medicine, The University of Chicago, Chicago, IL, USA ; Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK.
Insights
Obstructive sleep apnea (OSA) in children is common and affects multiple body systems. Treatment decisions for pediatric OSA require considering symptoms and comorbidities alongside polysomnography results.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Otolaryngology
Background:
- Obstructive sleep apnea (OSA) is a prevalent pediatric disorder characterized by recurrent upper airway obstruction during sleep.
- OSA is linked to significant cardiovascular, neurocognitive, and metabolic morbidities in children.
- The American Academy of Pediatrics recommends polysomnography (PSG) for diagnosing suspected pediatric OSA.
Purpose of the Study:
- To review the pathophysiology, morbidity, diagnosis, and treatment of pediatric obstructive sleep apnea.
- To emphasize integrating clinical factors with PSG findings for treatment decisions.
- To discuss current therapeutic strategies for pediatric OSA.
Main Methods:
- This is a review article synthesizing current knowledge on pediatric OSA.
- Key concepts regarding OSA pathophysiology, clinical impact, diagnostic criteria, and treatment options are discussed.
- Evidence for both surgical and medical management is evaluated.
Main Results:
- Pediatric OSA results from complex upper airway dysfunction during sleep.
- Treatment decisions should incorporate symptom severity, risk factors, and evidence of morbidity.
- Adenotonsillectomy is the primary treatment for hypertrophy-related OSA, with medical therapies like intranasal steroids or montelukast considered for mild cases.
Conclusions:
- Effective management of pediatric OSA necessitates a comprehensive approach beyond PSG.
- Early diagnosis and tailored treatment are crucial to mitigate long-term health consequences.
- Further research into optimal treatment strategies for varying OSA severities is warranted.
Abstract:
Obstructive sleep apnea (OSA) in children is a highly prevalent disorder caused by a conglomeration of complex pathophysiological processes, leading to recurrent upper airway dysfunction during sleep. The clinical relevance of OSA resides in its association with significant morbidities that affect the cardiovascular, neurocognitive, and metabolic systems. The American Academy of Pediatrics recently reiterated its recommendations that children with symptoms and signs suggestive of OSA should be investigated with polysomnography (PSG), and treated accordingly. However, treatment decisions should not only be guided by PSG results, but should also integrate the magnitude of symptoms and the presence or absence of risk factors and signs of OSA morbidity. The first-line therapy in children with adenotonsillar hypertrophy is adenotonsillectomy, although there is increasing evidence that medical therapy, in the form of intranasal steroids or montelukast, may be considered in mild OSA. In this review, we delineate the major concepts regarding the pathophysiology of OSA, its morbidity, diagnosis, and treatment.
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